ENBIS-13 in Ankara15 – 19 September 2013 Abstract submission: 5 February – 5 June 2013
The following abstracts have been accepted for this event:
Non-linear Mixed Model Approach for the Statistical Analysis of Stability Data
Authors: Heidi Wouters (Ablynx)
Primary area of focus / application: Modelling
Keywords: Shelf-life, Stability, Non-linear mixed model, Temperature excursions
Submitted at 11-Apr-2013 17:52 by Heidi Wouters
A commonly used approach consists of two steps where firstly each response is assumed to decrease with time through a first order kinetic relation which estimates a degradation rate. This model is fitted for each temperature resulting in an estimation of a temperature specific degradation rate. The second step uses the Arrhenius equation to fit the degradation rate as a function of the temperature. From this equation the degradation rate can be predicted for any temperature and hence a prediction of the shelf life can be obtained.
In this paper the two-step-approach described above is combined into an all-in-one non-linear mixed model having several advantages. In particular, the standard error on the degradation rate is much smaller since the parameter estimate of the degradation rate is based on all data. Moreover, more accurate standard errors are obtained since no linearization of the non-linear model is required. As a result, the all-in-one procedure has more reliable estimates of the degradation rate for intermediate temperatures. Moreover, the results can be generalized to any other potential stability batch since a random batch effect is included into the model. An R-tool is developed for computing shelf life at long term storage conditions and for potential temperature excursions based on the all-in-one non-linear mixed model.
Bayesian Assessment of Seismic Hazard Curves
Authors: Alberto Pasanisi (EDF R&D), Merlin Keller (EDF R&D), Gloria Senfaute (EDF - CEIDRE), Marine Marcilhac (Phiméca Engineering), Thierry Yalamas (Phiméca Engineering), Christophe Martin (Géoter)
Primary area of focus / application: Other: French special session
Keywords: Seismic risk, Bayesian analysis, Industry, POT models, Inference, Prediction
Submitted at 12-Apr-2013 09:38 by Alberto Pasanisi
Generally, data consists in values of the magnitude, experimentally observed or, in the case of ancient earthquakes, indirectly inferred based on historically recorded damages. The evaluation of the acceleration in a given point, caused by an earthquake of known magnitude occurring somewhere in the domain, can be made by means of a semi-empiric function, named the attenuation law, depending on the distance between the point under investigation and the seismic source.
In this communication we sketch a full Bayesian methodology for assessing the PGA distribution function (and thus the seismic hazard curves) in any point of a geographical domain. First (inferential step), the probabilistic model of magnitudes of the seismic sources will be assessed. This model, following the POT (peak over threshold) formalism consists in the distribution of the annual number of earthquakes exceeding a given magnitude, coupled with the probability density of the magnitudes, given that they have exceeded the threshold. Then (predictive step), the PGA is evaluated in the points of interest, taking into account the uncertainty tainting the parameters of the magnitudes' distribution and the attenuation law.
Finally, as a perspective we sketch some ways to build point estimators of the acceleration corresponding to given period of returns, based on Bayesian Model Averaging and Bayesian Decision Theory.
The Effect of Variance on Fuzzy Quality Control Charts
Authors: Nilüfer Pekin Alakoc (Atilim University), Ayşen Apaydın (Ankara University)
Primary area of focus / application: Other: Fuzzy
Keywords: Quality control charts, Fuzzy set theory, Variances of fuzzy numbers, Unnatural patterns, Average run length
Submitted at 12-Apr-2013 12:01 by Nilüfer Pekin Alakoc
Accepted (view paper)
Implementation of Steady and Second Order Polynomial Models Using R
Authors: H. Yagmur Gurkan (Hacettepe University Statistics Department), Gul Ergun (Hacettepe University Statistics Department)
Primary area of focus / application: Economics
Keywords: Dynamic linear models, Bayesian inference, Kalman filtering, Forward filtering backwards sampling, Gibbs sampling, R
Submitted at 12-Apr-2013 14:35 by H. Yagmur Gurkan
This study deals with implementing three different types of dynamic linear models such as steady model (random walk plus noise model), local linear trend model and combined model as a second order polynomial with a seasonal effect in R package dlm. Several methods such as maximum likelihood, forward filtering backwards sampling and Gibbs sampling are applied for each model. Datasets are generated to implement the steady model and the linear growth model. In addition, Turkey Cost of Living Index (Wage Earners) is considered for a second order polynomial model with a seasonal component. The estimations of the unknown observational and system variances besides the Kalman filter results are obtained in the study.
Use of the Sequential Nature of Bayes' Theorem in the Construction of Quality Control Charts
Authors: Haydar Demirhan (Hacettepe University)
Primary area of focus / application: Other: ISBA/IS Invited Session
Keywords: Credible interval, CUSUM, Bayesian estimation, EWMA, Quality control chart, Shewart chart, Tolerance interval control limits
Submitted at 12-Apr-2013 14:55 by Haydar Demirhan
The basic QCCs are known as Shewart Charts. The Shewart QCCs are constructed under various assumptions related with the considered quality characteristic. For example, if we are constructing an X-bar chart, we have the assumptions of normality and independence of observations. Stability of a process is evaluated by testing a hypothesis related with the type of constructed QCC at α Type-I error level. If the required assumptions hold, the size of the rejection region is α/2 on each side. The probability of a point within the control limits when the process is in-control is intended to be 0.9973 if a 3-σ Shewart chart is being constructed. For the cases in which required assumptions do not hold, various QCCs have been developed. The exponentially weighted moving average and the cumulative sum charts are some examples for those charts. As another point of view in the construction of QCCs, tolerance interval control limits have been introduced. Tolerance interval control limits are beneficial for taking under control the probability content at a specified level with a predetermined confidence.
There are also various approaches for the construction of QCCs from the Bayesian perspective. Most of the Bayesian approaches are based on the credible intervals. There are also Bayesian approaches for the calculation of tolerance control limits. These approaches are especially useful when the standard assumptions of the Shewart charts do not hold. Another approach is to use the sequential nature of Bayes’s theorem in the construction of Bayesian QCCs. In the literature, much attention has not been given to this feature in the construction of QCCs. For each type of QCC, either Bayesian or frequentist, there are some difficulties or limitations in the construction of control charts. When the Bayes’ theorem is used sequentially, the posterior distribution of the quality characteristic of interest is progressively updated; hence, information on the considered quality characteristic is accumulated after taking each sample from the considered process. As the result of this approach, more accurate estimates for the control limits are obtained, and small or large shifts are effectively detected. In addition, determination of some parameters by experts or collection of a preliminary sample is not required in this approach.
In this presentation, we discuss the sequential use of Bayes’ theorem in the construction of tolerance interval control limits for various quality characteristics. First, we mention previously proposed approaches for the Bayesian attribute control charts and the Bayesian X-bar chart for the exponentially distributed measurements. Then, we introduce the Bayesian tolerance interval control limits for the gamma distributed measurements, for which the distributional assumptions of Shewart charts do not hold. Lastly, we discuss the performances of the charts that are constructed by the use of the sequential nature of Bayes’ theorem.
A Comparison of Methodologies for On-line Batch Process Monitoring
Authors: Véronique Gomes (University of Coimbra), Pedro Saraiva (University of Coimbra), Marco Reis (University of Coimbra)
Primary area of focus / application: Process
Keywords: Statistical process control, On-line batch process monitoring, Two-way methods, Three-way methods
Submitted at 12-Apr-2013 17:49 by Véronique Gomes
Accepted (view paper)
Louwerse, D.J. and Smilde, A.K. (2000) Multivariate statistical process control of batch processes based on three-way models, Chemical Engineering Science, 55, 1225-1235.
Nomikos, P. and MacGregor, J.F. (1994) Monitoring batch processes using multiway principal component analysis, AIChE Journal, 40, 1361-1375.
Nomikos, P. and Macgregor, J.F. (1995) Multivariate SCP charts for monitoring batch process, Technometrics, 37, 41-59.